RetinALL IN ONE Face cream with stable form of retinal 0.1%

Our cream has been tested in an independent scientific center. RetinALL IN ONE Face Cream with a stable form of retinal 0.1% is encapsulated in cyclodextrin γ, thanks to the technology used, it provides stability for 12 months after opening.

This is a cosmetic for demanding, conscious customers. Balanced formula with minimal risk of irritation, thanks to the slow release system. The action of retinal improves the appearance of acne-prone skin.

Anti-wrinkle, reduces hyperpigmentation, against imperfections, suitable for sensitive skin.

It's a multi-tasking product that works on several levels:

• Reduces the appearance of wrinkles (slow aging)
• Improves the appearance of skin with a tendency to imperfections
• Reduces discoloration of various origins
• Contains antioxidants

Firmed, brightened skin with even skin tone. There is a visible reduction in fine wrinkles, imperfections and discoloration.

• The cream is suitable for all skin types, especially recommended for people with signs of aging skin, hyperpigmentation and those struggling with acne.
• The product may stain light-colored bedding and clothing.
• The product is contraindicated in pregnant women.

1. Wash your entire face with Ph.Doctor's Gentle Face Cleansing Emulsion.

2. Wait a few minutes until the skin is completely dry (5-10 minutes).

3. Apply a pea-sized portion of the cream to the forehead, both cheeks, chin, nose, and then gently spread over the entire face (initially 2-3 times a week at night).

4. 30 minutes later, you can optionally apply Ph.Doctor Lipid Face Cream.

5. In the morning, wash your face with Ph.Doctor Gentle Face Cleansing Lotion and apply SPF 50 sunscreen.

If redness, skin irritation or dryness appears, take a break for a few days until symptoms subside. Then return to the above care until you develop full tolerance.

• It is a precursor of retinoic acid (prescription retinoid), compared to retinol, which needs 2 transformations to the active form, requires only one transformation.
• Very active already in low concentrations.
• Stimulates the skin to produce new collagen.
• Has an antibacterial effect.
• Shows greater depigmentation effect than pure retinal.
• Smoothes skin texture by 21.1%.
• Improves skin radiance by 14.7%.
• Reduces the appearance of fine wrinkles by 12.5%.
• Reduces erythema.
• Regulates the sebaceous glands.
• Has anti-inflammatory effects: reduces inflammatory responses of interleukin-6, 1-alpha, prostaglandin-2.
• Reduces hyperpigmentation in people with melasma after 12 weeks.

• Has an anti-inflammatory effect and calms reactive skin.
• Strengthens the epidermal barrier.
• Increases skin production of ceramides by 34%, free fatty acids by 67%.
• Increases skin tolerance to retinoids, reducing flaking and dry skin.
• Reduces sebum secretion.
• Lightens hyperpigmentation, inhibits melanosome transfer into epidermal cells by 68%.

• Reduced area, number and contrast of dark skin discoloration (-14.5%).
• Reduced number of blemishes (-14.01%).
• Reduced visibility of skin vascularization, is an inhibitor of plasmin (an enzyme found in blood plasma, involved in dissolving clots).

• It is counted among the so-called melanoregulators, ingredients that unify the skin tone, allows the skin to restore a healthy glow.
• Inhibits the activity of the enzyme responsible for the formation of hyperpigmentation, it is counted among the so-called tyrosinase inhibitors (IC50 value 2.68 mg/ml).
• Brightens the skin.
• Reduces pigmentation spots.
• Reduces erythema.
• Reduces the visibility of pores.

In a study on a sample of 20 women aged 30-60 after 56 days:

• Reduces hyperpigmentation by 17% relative to placebo.
• Reduces the visibility of pores (-13%).
• Reduces melanin content (-7.5%).
• Reduces erythema by -7% (7x more than the placebo group).
• Brightens skin (+14.5%).