Temporary exacerbation of skin lesions with retinal
During the introduction of retinoids, a temporary exacerbation of acne symptoms may occur, for a period of about 12 weeks - during this time they should not be discontinued! Retinoids require patience, do not be discouraged! Note that exacerbation of skin lesions will not occur in everyone. However, its absence does not mean that the product does not work. There are skins that are more sensitive to changes in the environment in the sebaceous gland, as well as those that, apart from slight drying of the skin, will not experience any major inconveniences. Possible exacerbation will not necessarily occur after the first use, it may appear after 2-3 weeks. Therefore, it is important to simplify care in the initial period of building tolerance (so-called retinization) despite the lack of adverse effects and observe the skin before introducing further active substances.
The exacerbation that may occur results from a sudden change in the microenvironment of the sebaceous glands, which is unfavorable for the development of Cutibacterium acnes - it plays a major role in the development of acne. The bacteria disintegrate and numerous inflammatory mediators are released, provoking the exacerbation of acne symptoms. Additionally, retinoids accelerate the renewal of the epidermis, so any inflammatory changes will be "lifted" to the surface of the skin. There are studies that have confirmed that retinal causes a decrease in sebum secretion, normalizes the process of keratinization of the outlets of pilosebaceous units (preventing the formation of comedones), limits the possibility of the development of C. acnes in the sebaceous glands. It has anti-inflammatory effects due to the inhibition of chemotaxis of neutrophils and monocytes, stimulation of Th lymphocytes and phagocytosis of C. acnes by neutrophils. Additionally, by limiting the synthesis of MMP and TIMP, it inhibits the degradation of the matrix, bringing improvement in acne lesions and preventing scarring. You can minimize the risk of acne symptoms getting worse by properly introducing retinal into your care. First, you should focus on maximally rebuilding the lipid barrier, calming inflammation, moisturizing and regeneration. For a period of 3-4 weeks, give up all acids, peels, exfoliating products and start your facial care with: Ph.Doctor Gentle Face Washing Emulsion , Ph.Doctor Tetra C Serum , Ph.Doctor Lipid Face Cream . Also remember about a cream with SPF 50 UVA UVB filter for the day - choose light emulsions without alcohol. After 3-4 weeks of rebuilding the lipid barrier, it's time for RetinALL Ph.Doctor - proceed as follows: for 2 weeks use RetinALL 2 times a week, for the next 3 weeks 3 times a week, for the next 4 weeks 4 times a week, for the next 5 weeks 5 times a week. We recommend starting with FACE&BODY RetinALL cream with a stable form of retinal 0.05% and the "Sandwich Method" to reduce the risk of redness and irritation - link https://phdoctorlab.pl/blogs/baza-wiedzy/skora-wrazliwa-naczynkowa-a-krem-do-twarzy-ze-stabilna-forma-retinalu-retinall-in-one-0-1-krem-ze-stabilna-forma-retinalu-face-body-retinall-0-05-zastosuj-metode-kanapkowa
